More research needed for cannabis use in PTSD treatment

More research needed for cannabis use in PTSD treatment

Chandni Hindocha Two recent studies concluded that although interest is strong, more research is needed before clinicians make treatment decisions regarding cannabis use in PTSD. Although findings published in Depression & Anxiety indicated that marijuana may increase suicidality in military personnel with elevated PTSD symptoms, findings published in Journal of Dual Diagnosis indicated that cannabinoids may reduce PTSD symptomology. Shows potential “There are shifting legal and political moves ongoing around medical cannabis around the world, and one of the main areas that has received a lot of attention, mostly because of the campaigning of military veterans to get access to medical cannabis, is PTSD,” Chandni Hindocha , PhD, research fellow of University College London, told Healio Psychiatry . “PTSD is also a hugely debilitating disorder, and current treatments have limited efficacy and also side effects, so the need for a novel treatment is high.” Hindocha and colleagued conducted a systematic review and examined the quality of available clinical evidence on the effectiveness of cannabinoids for PTSD treatment. The researchers evaluated the reduction in the severity of symptoms in studies published until December 2018 where a patient with PTSD was prescribed/used a cannabinoid to reduce PTSD symptoms. Cannabinoids included nabilone, THC, CBD and whole-plant cannabis products (herbal and resin). The review yielded no randomized controlled trials; therefore, these findings were based on evidence from observational and retrospective studies and case reports. Overall, 10 studies were included in the review, one of which was a pilot randomized, placebo-controlled clinical trial that investigated nabilone in a small sample over the short-term. Although all studies had medium to high risk of bias and were low quality, the results indicated that cannabinoids may hold promise for PTSD . The investigators found that cannabinoid use appeared to decrease PTSD symptoms, such as sleep disturbances and […]

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